Originally Posted by: KasperowIn my opinion, it handles Humbuckers very well. I only have guitars with Humbuckers (except for my acoustic, for obvious reasons), and they all sound amazing through the Mustang II. Most of the time, I play an Epiphone Les Paul, and there's pretty much nothing it can't do with the Mustang. Except for sounding like a single-coil guitar, of course (but that's generally impossible for Les Pauls without the newer Coil-Splitting function).

The best thing you can do is to try the amp with as many different guitars and settings as possible. After all, the only one who can decide, what gear you buy, is yourself :)

Thank you for your feedback. For sure I will try this amp at the store before taking my final choice of amp.