I've owned a few different tube amps, and each had a sweet spot for me. 2 fenders (Super Reverb, Deluxe Reverb), Gibson Falcon, Epiphone Valve Jr., and my current Egnator Tweaker 15W.
For clean sparkling, the Fenders just ruled! With decent pedals, they rocked as well, but their effects loops were always noisy, and the amps seemed to wear out tubes quickly. Expensive these days to re-tube. Also often needed bias adjustments if you traveled much with your amp. My Super Reverb was a 4X10 combo, real back-breaker, but it could really cut through for a combo. Deluxe was more versatile, single 12", smaller output tubes, not a back-breaker.
The Gibson Falcon was a fun amp, single 12", trem and reverb. I miss it's trem often, there's not much to compare to a good tube vibrato. Very limited tone-wise, sometimes picky about pedals, no effects loop. But it had a great sound with a 335 Epiphone hollowbody. Smaller tube complement, tube rectifier.
The Valve Jr. was only a transition amp to get back into playing, but there are a lot of mods to hot rod it, and it has a simple two tube complement. Mine is still in pieces, as I figure out how I want to mod it.
The Egnator Tweaker is a real versatile little gem. 5 tube complement, very flexible tonally, and it does have an effects loop. Found a used one on Craigs' list for $250, maybe the best money I ever spent. Seems to take pedals well, and I can get close to the sound of many different amps.
Not I real fan of the modeling amps, so far. They have improved, but still, somethings missing to me. I have heard both a Line 6 and Fender tube version. They have their place, and I can see the value in them. Especially since reverb, delay, and trem are often thrown in the package. Still, I would rather gear up to nice external effects pedals these days, or buy a vintage amp that already has trem and reverb.