When I was in my twenties (oh lawd, sooooo many years ago.... hehe) I was quite the ladies man. You know why? Because I had NO FEAR at all. I would ask anyone out. (I'm sure being chemically enhanced had a lot to do with my complete lack of inhibitions and I am NOT recommending the same) It simply didn't matter. If I thought a woman interesting, I would walk up and start talking to her.
But you want to know what the great equalizer is? Humor. Seriously. If you can get her to laugh, things will generally go your way. So...open with a joke or something. You work with her so you have a lot of shared experiences and you know the same people. Fertile ground for humor.
Good luck. And to add to what Fret said "I double dog dare you.'" Now you have to do it. :D
[FONT=Tahoma]"All I can do is be me ... whoever that is". Bob Dylan [/FONT]