Well first and foremost for me nothing beats gettin down and dirty with the blues...and the screamin tone i get from my strat with some texas specials or some fender custom shop 69's make just melt my ears...my favorite players SRV, hendrix, clapton in the latter days, all excellent players dig the singles, but then again i love clapton when he was swingin bucker axes, jimmy page with his lp, b.b. king w/ his lucille, honestly it's the man behind the axe that truely makes the sound and not vice versa! But when my hands grace a strat it just feels right...So with that said i guess its more a question of what sounds best with you makin the noise...just in my honest opinion ;)