There's no way in hell to pick 5, but here are some of my very favourites (in no real order, other than the order I remembered them).

Kurt Cobain
Thurston Moore & Lee Ranaldo (and Kim Gordon; I can never tell who plays what)
Jimmy Page
Jimi Hendrix
George Harrison & John Lennon
Keith Richards & Ron Wood
John Fogerty
Pete Townsend
Robbie Krieger
Tony Iommi
Jerry Cantrell
Jack White
Angus & Malcom Young
David Gilmour & Syd Barrett