Sounds like drop C tuning.  I'm not sure about the rest of the strings.  But if you tune your low E down 2 whole steps to C you can play the intro like this.

|---------------------------------------------------|
|---------------------------------------------------|
|-----7b8r7-------------5---8-10-8---------------|
|-------------8-------------------------------------|
|----------------5----------------------------------|
|-0------------------0-----------------0-----------|

Then once the groove gets going the main riff is something like this.

|----------------------------------------------------|
|----------------------------------------------------|
|-------------------5----------------------7--------|
|-3-3-3--------------3----------------------8------|
|-1-1-1-------3-6-------------8-10-8-6-----------|
|---------0----------------0------------------------|

But the tuning could be all the strings dropped 2 whole steps.  Or just the low E dropped 2 whole steps to C & the other strings dropped 1 whole step, kind of like a drop C tune.  Like this.

D |-------------------------------------------------------------------------|
A |-------------------------------------------------------------------------|
F |-------------------------------7------------------------------9-----12--|
C |----------------------------------7-----------------------------10------|
G |-10-10-10-0-----0---5-8-10------0-------10b(12)r(10)-8-------------|
C |-10-10-10-0-----0----------------0------------------------------------|

Hope that helps!