A buddy of mine from an old 80's hairband.www.julliet.com uses a Line 6 half stack. They got a great tube sound for something that doesn't have a tube in it. But he will still to this very day swear by his modified Marshall's that he uses for recording.
Anywhoo....The Spider 212 is a great amp, but for a little extra you can now get the Flextone II model which is even better. They drop a few hundred bucks to $599 or less. I saw them the other day at American Music in Orlando for $499.