I went multi and never went back.
I still can't believe I used to have about 10 pedals all wired to a board with either a bunch of 9 volt batteries or a bunch of huge power supplies taking up most of the room.
The best thing about multieffects pedals for me is the midi.
When your drummer is experience in keeping time to a click track, you can pre-program all your changes ahead of time and never have to remember which pedals to hit.