There's a flanger, phaser, distortion and possibly something like a Lesley amp or tremolo on the riffs that rise and fall in pitch.

I think the guitar that starts where you write is basically really heavy distortion and reverb. There may also be an octive pedal involved or something that doubles the notes.

I think there's also considerable post production on the recording itself but could be wrong on that score.

It definitely isn't something you're going to replicate with just a fuzz, although I suppose you could get the distortion from a fuzz pedal.