Hi Brian... hopefully we're talking about the same amp here. If so, you should have six knobs and a "drive select" button. Looking at the amp front on, start from the right with the tone knobs, Bass, Middle, Treble. Turn all those so that they are half way (probably "5" on the dial).
Turn the "drive volume" and "gain" knobs to one, and set the "drive select" button in the out position.. so if its pushed in, push it again so its popped out.
Lastly, set the normal volume to 1.
Now plug in your guitar and turn your guitar's volume knob or knobs to full volume.
Turn up the "normal volume" just a bit. You probably won't hear much sound, or maybe no sound at all. If there is no sound at all, try turning the "gain volume" up a little.. you should hear the guitar now.
To keep the guitar sounding clean, you want to keep your "normal volume" higher than the "gain volume". Hopefully you can use just these two volume controls to get a nice, clean, undistorted sound.
Experiment with the drive settings by first setting up a clean sound described above, and then turn up the "drive volume" and also experiment with the "drive select" button. The more drive you want, the higher you'll need to turn up the "drive volume" and the "gain volume", leaving the "normal volume" fairly low.
Keep in mind that amplifier is not a tube amp, so the "gain" and "drive" is simulated... you're not really driving tubes hard to get that smooth, warm-fuzzy overdrive sound that a real tube amp would have. But the simulated drive might be good enough for now, or you could buy an overdrive pedal if you wanted.
Hope that helps...