Personally, although I find it hard not to play for long periods of time (I tend to suffer from withdrawl :) ) When I do eventually get to return to it, i find I'm more comfortable with it, no, that's not right, I find it sounds better. Whether this is because I'm less critical of myself, or because I'm glad to get back to it, or because I have had ideas or thoughts bubbling up inside me while I've been away and unable to release them, or just because I've taken a break, and are more rested.
However, I'm not talking from a long term standpoint here, I've never been away from the guitar for more than three weeks, I can imagine, after a few weeks I'd lose some of my technique...I know that currently I do lose something in speed and accuracy, but that's trivial to what I regain in the natural fire for the music.