You should download a trial demo of "AmpliTube" or other similar program and try out the different combinations of amps and cabinets. You'd be amazed at what a subtle difference just a change from a 4X10 to a 2X12 cabinet can make.
You can also try different micing techniques and effects pedal combinations.

It's not the real thing, but it comes pretty close to emulating what you sounds you'd get.