It depends what you mean... Picking and legato both have their place, and I'd use both in a solo for variety anyway. I favour legato, but only because picking really fast can sound a little mechanical (at least when I do it!)

The easiest place to start is probably improvising with a minor scale and adding some diminished stuff.

Personally, I find I get a good fusion sound using Dorian and the whole/half diminished scale...