Major score! :D

1. Don't try to use all of them together - you'll just get seriously tangled up and distracted by all the weird things you can do with the knobs. And several of those pedals are variants of the same thing.

2. Use the A/B switch to send your guitar signal to the tuner [u]or[/u] to the effects. This allows you to tune silently, and it takes the tuner out of the signal chain when you don't need it. Later, when you have a better handle on what those pedals can do, you can try setting up two different signal chains built up from different pedal combinations.

3. Start out with just one pedal, and spend some time with it. The 'kid in a candy store' approach will not be productive. I'm not familiar with Line 6 products (I'm an old fart - modelling annoys me no end), but if those are multi-FX boxes, you can use them to find out what sort of patches sound best to you. Then you can reconstruct those patches with individual pedals to get better tone.

4. Have fun! If hooking everything together and tap-dancing on all the buttons brings you joy, then do so. After the novelty wears off a bit, then you can go back to step 1 and sort 'em out.