they sound differnt with and without a slide.
but im not sure if this is what you are asking.
you refer to the use of slides in metal, do u meen just sliding your finger up the fretboard or using a slide (metal or glass tube). i am not aware of them using slides (the metal or glass tubes) in metal music. they do oftern use the whammy bar, which gives similar efffect.
sorry if this isnt helpful i dont reallly understand the question :o