Originally Posted by: PRSplayaCheck out >THIS< post by Lats. Some very usefull info there.

Here's what I personally do... I start with all tone controlls at 12 o'clock. Since my favorite part of a guitars tone is baseball bat to the chest midrange punch, that's where I start. I get real familiar with how the mid control changes the tone, and what it's characteristics are. Once I find a nice place for my midrange, I'll usually move on to the treble next. I'll do the same thing here... get to know it, and how it reacts with the other controlls. I usually add just enough treble to give some clarity and bite, but not so much that it causes ear fatigue. Then I'll move on to the bass. Thunderous bass is nice, and sounds good, but the fact it... it will kill your tone in a mix or a band situation. I usually only add enough bass to fill out the low end a bit. Also, try rolling back on the gain a bit. Using too much gain can really muddy up a great tone, and make it get lost in a mix. Set the gain where you think it sounds best, and then roll it back just a touch and leave it there. Also, if you have a tube amp, your best tones are gonna come when you really have it cranked up, so just keep that in mind.

One more thing to pay attention to... Where you're standing/sitting in relation to your speakers will greatly effect how you perceive your tone. Tilt your amp back so that the speakers are pointing more towards your head, or walk out infront of your amp about 10-15 feet to hear what your amp really sounds like, and how people that are listening to you hear it. ;)