I'd look into some of the blues and country styles. A lot of their solos use 2 or 3 strings at a time as lil mini chords in a sense. People such as Mark Knopfler (Dire Straits), Billy Gibbons (ZZ Top), and a bunch of others...hell almost everyone uses this every now and then. But like was said above, yer gonna need to know yer chords and scales.
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