I love George L cables myself. You can tell the biggest difference when going straight into an amp, but once pedals and more cables are introduced, the difference it becomes less apparent. When recording, I only use George L's, because they do add some clarity and openness to the signal. When jamming on my live rig (not recording) I use a mix of cables. I find that my ears are quite sensative to the high end, so a guitar straight in with a 10' GL adds too much for my ears. Even with a 20' planet waves cable from guitar to pedal board, a mix of ~6" livewire/GL/dimarzio cables connecting pedals, and a 20' GL cable from board to amp, I have the presance knob completely off, and the treble knob around 11 o'clock. Some of the clarity is lost, but the trade off is minimal. It all depends on what sounds best to your ears.