I'm pretty sure I'd do the same - just pack up my guitar and gear and hit the road. I doubt have no worries about work or things like that.
I might struggle with leaving my girlfriend and the places I love to just spend time, but other than that I have no real ties to where I am.
Admittedly, you're never quite sure how you'll react to a situation until you're there. I might actually suddenly realise that I just couldn't leave here. All things considered though, I'd more than likely take that chance. Friends and family would understand and, so long as I could still find some where special to me, (corner of a bus, etc.) then yea, why the hell not?!!!!
Anyone else? Anyone who wouldn't?