It's probably your guitar causing the noise. What pickups you using? If they are crappy cheap ones you can be guaranteed buzzing noises, if they are a good set then maybe you don't have them earthed properly. Do a search online for installing humbuckers and single coils, there should be diagrams that will show how it should be done. I had that problem on an old Charvel I had, went away when I upgraded the pickups. The other potential problem would be if you have a lot of electrical equipment in the room you are playing in, or are sitting too close to the amp or especially if you have a tv or computer with an old style moniter turned on close by. The photons spilling out from the display cause havoc with electrical pickups and become amplified through distortion and overdrive. Check these first before you look at your pedals/stomp boxes - those things are usually pretty reliable.