I wouldn't worry about getting the best possible solo sound out of your equipment, your probably never going to manage it. You can have a £2,000 signature ibanez and a custom mesa boogie triple rectifier, it will still only be 1 sound. I usually just add a touch of reverb and delay... then vary the gain depending on the music. Depends entirely what the solo'ing is for. Blues/metal/rock etc.

- J