Pickups are pretty much personal preference, you can use just about any electric pickup in any electric guitar, you may need to do a little body work to make them fit, or replace the pickguard and whatnot. Just make sure the pickups arent unbalanced, as this can cause some problems with output. and if your going for like SSS or HSH you gotta make sure that the neck and bridge pickup are matched so they hum cancel when you switch the NM and MB on in pairs. what else, oh yeah, if you like distortion, go with a high output pickup in your bridge position. Ive heard of pickups nicknamed "MOther Buckers" anyone else know anything about those?

It also comes down to personal preference and what kind of sound you are going for. Some pickups are made to rock hard, like active pickups like EMG's or SD Hotrails, and some are made to groove and blues with.

hope that helps... latah