those replys pretty much covered it.

I noticed my neck humbucker is more bassy, and not as sharp as the brigde pickup. I like the tone the brigde pickup gives me more.
I rarely switch pickups or use both of them.

As for my other guitar: 3 single coil pickups.
I use the brigde and middle pickup for my clean sound, and the brigde only for distortion.

why do I have neck pickup anyways lol :)