I don't know what the Parker Fly custom is like, but the DiMarzio X2N is the most extreme high-output passive pickup out there! It will not play cleanly - it was designed only for overdriving any amp input stage. A very single-purpose pickup.

The Fred is similar to the PAF Pro, with a little tweaking to bring out the harmonics. It's not quite as dramatic as the Tone Zone, which makes it easier to get along with. I think it would work well with a Humbucker From Hell, which actually is a very sweet-sounding pickup - smooth and warm when played clean, it cranks up nicely when you wanna play dirty.