Go direct and use an amp simulator or plug something like RedBox Cabinetulator into your send/receive. But take an amp too. You can always route the guitar signal back out to the studio through the amp and mic it a second time on a new track. About the only time you need an amp for sure is when you need the feedback.... although you can get this direct too just by using small speakers up close to the guitar.
You should look into Amplitube if you record digitally. You can simulate anything from AC-30's to Fender Reverbs to Marshal JC-800 plus it gives you an auto wah, echo, any cabinet you want etc...