1. Neil Zaza
2. Steve Vai (of course)
3. Nuno Bettencourt
4. Good ol' Satch
5. George Lynch
6. Tony McAlpine
7. Vinnie Moore (yes, I am old enough to remember his Pepsi Commercial)
8. Vernon Reid
9. Paul Gilbert
10. Marty Friedman
11. Jason Becker

Admittedly this list is a lot better than the other ones in this thread, but a couple things.

Neil Zaza, Steve Vai, Satriani? They're good guitarists, but they only briefly played metal at all.

Also, for fans of Tony Macalpine and Vinnie Moore, I have good news sort of. I HEARD that we might be getting their album pretty soon (they've been working on one together for a while).

I also think that Mattias Eklundh needs some kind of mention. His technical skills don't shine out amongst metal shredders like Rusty Cooley, Tony Macalpine, etc, but he is very original, especially for a metal band.