The standard floorboard multi-effect processors that are mentioned in this type of discussion are:

Line6 POD
BOSS GT-6
Digitech RP series (I think the 500 is the best so far)
Yamaha DG Stomp

Check the above models out. All of them offer multiple effects in one convenient package. Some have built-in expression pedals that can control volume, effect mix/level, wah, etc. Some have MIDI capabilities. I think all now have amp modelling.

My personal fave is the BOSS GT-6. It has all the above features that I mentioned and even has wah modelling. If money truly is no object, I doubt you'll be disappointed. It basically combines every BOSS pedal and some non-BOSS pedals into one unit. No matter what everyone else says about the presets, the built-in sounds are amazing, if you know how and when to use them. Plus, it comes in a wicked gold colour.

I've also heard that the new Digitech was supposed to have a built-in talkbox...haven't heard any more news on that.

This may very well spark a stimulating discussion of multi-effect processors... I can't wait!!