I keep a couple of axes strung with D'Addario EXL110 (.010-.046) for ocasions when I wanna get slinky. I keep my main guitars strung with EXL115W (.011-.049 with a .021 wound G). I play mostly rythym, and heavier strings give much better tone. Next string-change, I'm taking the step up to EJ21 (.012-.052). I don't do 3-fret bends, and none of my guitars have a whammy bar. I insist on huge tone, and killer sustain without having to resort to overdrive or feedback. As with any equipment choice, its a deeply personal thing.
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