I have a Mesa Boogie Mark 3 Simulclass and it kicks anything else I've played into touch, including Marshalls and Fender, Laney, Trace Elliot, Line 6 (yuck) etc

I use no additional effects, just me trusy Boogie and PRS and I'm always getting complimented on my stage sound. if you want smooth creamy ass kicking distortion then this set-up gives you it.