who do you want to sound like? do you need a floating tremolo syetem (Floyd Rose) , standard tremolo , or no tremolo (tun-o-matic bridge) ..
are you going to need a 24 frett neck? or will a 22 frett satisfy you?
what about the pickups, single coils or humbuckers?
what about the wood type? did you know that it doesn't only affects the weight of your guitar, but also affects the tone?
you should answer these questions first to choose the right guitar for you, because there is nothing called 'The Best Guitar'