Personally I've just started experimenting with tuning all in 5ths (EADGCF). I'm finding it hard to learn the new chord shapes but it does have some advantages. For instance I love natural harmonics, for every string you can get a major arpeggio from harmonics just by stopping the 5,4 and 3rd frets. EAD give you all the chords you need for A major, GCF gives you all the chords you need for C major. Neat huh? Another advantage is that whillst staying in a given position your fingers can get one note higher in pitch.
There are disadvantages however; if you want to play chords which have more than one duplicated note sometimes the fingerings can become tricky.
Do you guys play in other tunings? What do you think about this?
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