"Dozens of people spontaneously combust each year, it's just not that widely reported".
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... But at the same time, if you're like me, you might like adding and taking away effects throughout a song. Normal chord sound, then with delay, then to a solo sound with no delay, then with delay and wah, then take off the wah, then take off the distortion to get back to normal, but add a flanger for a certain chord section, etc. If you do that sort of thing, you end up having to program a whole lot of different channels of the same sound with different effects added. Generally the theory goes that Single effect boxes provide the most quality sound, whereas multi FX boxes provide a better mix, and often create a more unified sound, with more possibilities in variation and completely different sounds changed quickly.