I take it you are meaning how will a humbucker sound in your strat? Well it will change the sound somewhat depending on what particular humbucker you choose, it could sound thicker with less high frequency, more toward the Les Paul type of sound, or depending on the pick-up, more toward the 80's shredder type of sound, your sound will depend largely on type of guitar, body wood, bridge type, etc, pick-up selection depends on what you are looking for, their are just dozens of choices, also many stacked humbuckers that look like single coils, and have everything from a noiseless single coil to hot humbucker sound. Something to always remember with any new gear, you will still sound like you, and the guitar is one half of the sound of an electric guitar...............