I have VERY small hands. I mean, my hands are equivalent to the average female freshman, and I'm a male high school senior! BUT, I don't think that hand size matters as much as some people say it does. Even with this little hand and short fingers, I still use my thumb a helluva lot for chording (like 5, x, x, 4, 5, 6 = Amaj7, thumb on low E). I can reach from the 5th to the 11th fret comfortably. If I needed to go from the 5th fret to like the 14th, I'd just play the A on the B string, at the 10th fret ;) I think large hands/long fingers can be a disadvantage, especially when it comes to chords, because sometimes cramping a bunch of fingers into a 2 or 3 fret span can be difficult. A friend of mine has really long skinny fingers, and it's hard for him to do some chords I do because his fingers just won't bend like mine. It's all about flexibility...