Doing the DIY home stuff latency was sometimes a real problem no matter what DAW we used there was always some sort of issue to overcome, sometimes the equipment we had was better and it was less of a problem. When i've used one of the BBC recording studios they were using protools but all of the equipment was of very high quality and latency was never an issue to be honest.
When using protools or another DAW it really does come down to how good the rest of your equipment is including your mac or pc, it needs to be up to the job for it all to work properly.
