A strat with a USB ouput...now I've seen it all!

In general, a fender squire strat would be a good place to start for blues with an electric guitar. The USB thing seems gimmiky to me. I suggest you go to a store that stocks squire strats and try one out. You can get kits too that include the guitar and an amp. They may also include an amp cord, electrnoic tuner, guitar strap, and pick!