It's all about what suites the song, and what feels right to you. If the programmed drums and bass suite what you want, then go for that. If a more live feel is what you are after, then use players.

However, in the case of live musicians SO much relies on their playing and how it's being recorded. I believe a great player can sound good anywhere, where as an OK player won't necessarily sound great with amazing gear.

It's honestly up to you. ;)