I've got fairly little hands... um... I'm ok with them, cos they're literaly like rubber... um what do you have a problem with in particular? If stretching for certain chords is a problem, just keep trying, your hands should "stretch" gradually (but if it starts to hurt stop and try again later)... I mean with time it gets better...
If your really find it a major problem then maybe you should consider guitars with a shorted scale lenght....