That's the stuff you'll figure out. Anybody can play random notes on a scale and not sound bad. But what you learn is what to do when and how it relates to what you want to say. These are things that you'll only figure out over time, and if you're remotely like me they'll just come to you out of nowhere. "Ooooo... I can do this can't it?!?!!" And low and behold you now have added unison bends or string rakes to your pallete.

I don't think it's so much practice as a familiarity thing. You'll do things without thinking yet have have a better sense of how it will fit the song as a whole.

Practice will give you to technical skills to do the things you want, but the learning aspect of this happens to you.