Sure thing. I am not sure how great that will sound honestly. The whole essence of a pre-amp is to create a warm, tube "mediator" between your mic and interface. This can make the difference of making a cheap mic sound, well, not cheap.

If you visit the link below, there is a track on my myspace page called "Full Suspension." All the guitars were recorded using a POD XT live into a FOCUSRITE preamp. No micing.

Douglas Showalter MYSPACE PAGE: Listen to "Full Suspension"

Happy Noise Making!!!