I personally love Open-G tuning. Number of reasons why i started playing in it, one of them is slide guitar. I mean to play slide open tunings are really good.
It takes some time to get used to the chords and to the scales in it. I mean I'm not a professional so i still see patterns on the fretboard, i don't think i will ever be able to actually see intervals the way pros do.... But even with scale patterns its relatively easy to switch from standard tuning, they just shift 2 frets higher on 1st, 5th and 6th string.
I notice some things are easier in Open-G than in standard tuning, especially everything related to playing the blues, for me anyway. I know some people who been playing blues in standard tuning might disagree with me, that's why i say "for me anyway" :)