I should probably get both guitars professionally set up to make the action as low as possible without buzzing. That would make it easier. The Strat plays well as-is, but I'd like to go as low as possible w/ the action on both guitars.
And Kevins' reminder that you don't necessarily need all six strings is a good one- in fact, in my opinion, 6 strings strummed all at once on an electric guitar sounds very muddy.