I have ms also and it messed up my timing and I would miss strings if I was fingerpicking. Somedays even holding on to a pick was a chore. I also had 3 fusions on my neck so my left hand didn't feel much. I got so frustrated that I didn't want to play at all. It took me 15 years to get back enought feeling so I could play again. There are quite a few others on here going through similar problems. I guess the big thing I keep telling myself is Don't quit! That's something you can't let yourself do. For a long time I let ms dictate what I was going to do with my life, but now I don't let it run my life at all. If I want to play guitar, I'm gonna play to the best of my ability come hell or high water! There are times I sound so bad missing all kinds of notes and other times I play so good I would have no trouble keeping up with anyone. I know it's frustrating as hell at times but keep playing! Send me an e-mail if you want, I do know what your going through and it ain't fun but don't let ms tell you you can't play anymore because you can! Take Care-John