I dont know, I use the other two frets alot, espeically with other peoples stuff. but for certain genres and styles 22 could be fine such as rythm players or jazz but i really like having the option. also i fonud this article about it
http://www.edromanguitars.com/newsite/techarticles/22vs24.htm
"We forgot to call Dylan" "Who the F*ck is Dylan?" "oh, I mean xDylanx" " oh yea we forgot to call him"