I'm not sure what to tell you. I was having problems with dropouts and the audio "skiping" (best way I can put it) while recording, but then I started messing with the settings (don't remember which) and it works fine now. I'm recording at 44.1khz, which I think helped a bit. I also went through and made sure nothing was running in the background that didn't need to be. There are also a few more things you can do that they talk about on the presonus site. I'd suggest checking it out.