After reading about what SRV did, that's what I put on my Strat, but I hate it (that Strat, not the strings, and not Strats in general by any means) because it has a Floyd Rose bridge! Floyd Rose sucks. I have to keep it downtuned to C# or lower so that the stupid bridge won't pop right off! I guess I have to get more and beefier springs for the back cavity. Still haven't gotten around to it... and downtuning low and barfy is alright by me (Iommi is one of my Top 3 guitar heroes) but it sounds like crap on a Mex Fat Strat. Grrrrrrr... I think I'm going to give that guitar to an unsuspecting buddy and then find something with a nice beefy hardtail set-up to put 13s on... or better yet, something with a Kahler.
I recently got a second guitar... the freeloader that bunks at my parents' house gave it to me. Some obscure early 1960s Japanese model... the brand is "Norma." It has P-90 pickups and seems suited for surf guitar and that sort of thing. I guess they used to be part of the Crown company that also used to include what are now Tama drums. I had a spare set of 10-46 lying around so I put those on that. Easier to play and sounds/feels decent... but nothing compares to those 13s!