You can go 2 routes, one is to plug your guitar through an existing amp/modeller and then into the computer (using the headphones/line out in the amp/modeller) or plugging your guitar straight into the device through a mic input and using a software modeller (which can be more flexible and changeable but less authentic).
I'd recommend getting a toneport instead of a fancy sound card.
Worst experience i've had with a sound card was a professional one in a PC that i was using to record a voice over for a documentary (not my voice :)) and it was a top of the line cable and a sure SM58 and a top sound card, and still - totally bad quality. ended up using the camera to record the voiceover!