If you adjust the pickup closer to the strings, you will increase the volume. However, if the pickup is too close, the magnet will dampen string vibration and you will lose sustain. If the pickups are too far away from the strings, you will have low volume and the pickups may move around if the spring is completely uncompressed.
My Strat has fixed magnetic pole pieces so the two screws on the side of the pickup are used to adjust pickup height and tilt. My Les Paul has adjustable poles, so the screws are used to adjust height while the poles are used to balance the signal between the strings.