The harmonised scale..
If your chord progression is in Gmajor - use the modes of Gmajor - or to get a bluesy feel - use the blues(y) scales in Gmajor (the minor a, b, e scales + arpeggios) and D mixolydian mode, - though all of this sounds a bit prescribed tbh - particularly when using god awful major seventh and lydian mode together....
Everything you do in it - is pretty predictable, so you have to reach outside the key (passing notes, Gmajor (ish) tapping riffs and so forth)...to get any originality in your playing (or listen to bulgarian wedding music?).
You can also change keys...
There are ways to use modes that I don't understand such as pitch axis (using the same modal root note but that root note is in different keys) - or mixing modes (i.e. mixodorians - combo of dorian and mixolydian etc).
It is interesting reading the preface to Joe Satrianis Surfing with the Alien to see how he used modes in his early albums
Hope this helps....