Too much of anything is bad for you. I've seen arguments among major serious tone-freaks about nitrocelulose sounding better than polyurethane, but I don't think it makes any difference on a solid-body axe. I suspect that by the time you put enough stickers on the front to deaden the tone, you'd have problems getting at the strings. I avoid 'em myself, 'cause they look just as "me too" as the bitch-brand tatts so many women are wearing now.